Case Studies · queryDNA in Production

The results speak for themselves

Results page updated · compiled by the SEMoptimize founding team · client identities generalized by vertical

SEMoptimize's queryDNA rebuilds have produced documented results across verticals: a national at-home healthcare provider grew qualified requests 99.94% per month while cutting monthly ad spend 29.85%; an insurance lead aggregator grew profitability 589.14%; an e-commerce client compounded to 701.01% revenue growth over five years. Every number below comes from client account data.

National at-home healthcare provider — flagship case study

Flagship · National At-Home Healthcare Provider

The SEMoptimize way: a complete re-engineering

We completely re-engineered every aspect of this client's digital marketing architecture. Data built to feed optimization — delivering not just leads, but the right leads at the right cost.

Account architecture — before → after

Keywords

Before
6,660
After
813,952

Custom ad variants

Before
2,067
After
263,367

Keyword ad groupings

Before
320
After
131,764

Full-funnel transformation — up where it counts, down where it costs

CTR
+14.37%
CPC
−26.04%
Ad spend
−29.85% (−$164.6k/mo)
Qual. requests
+99.94% (+2.33k/mo)
Conversions
+77.81% (+1.41k/mo)
Cost / qual.
−64.91%
Cost / conv.
−60.55%

More client results

Six more verticals, same molecular method

Insurance Lead Aggregator

Historic profitability, even at massive scale

In one of Google's most cut-throat verticals, queryDNA optimization didn't just compete — it nearly 7×'d profitability while pushing lead volume up and cost-per-lead down.

  • +589.14% profitability
  • +215.15% lead volume
  • −4.50% cost-per-lead
001252503754100queryDNA launchJanMarMayJulSepNovConversions (K)Margin index

Lead Generation

We out-optimized a top-100 Google advertiser

Even for one of Google's 100 largest ad spenders, we found the room others miss — rebuilding the DNA of every impression to triple profitability at higher lead volume.

  • +301.70% profitability
  • +135.29% lead volume
  • −18.32% cost-per-lead
001252504755100queryDNA launchJanMarMayJulSepNovLead volume (K)Cost per lead

E-Commerce

72% in year one. 701% over five.

queryDNA optimization compounds. A standout first-year revenue lift was only the start — five years of relentless iteration turned it into 701% growth.

  • +72.26% avg YOY revenue
  • +701.01% 5-year revenue
002175435065258700queryDNA launchJanMarMayJulSepNovRevenue ($K)% YoY growth

National Pediatric Hospitals

The right answer for every search, at scale

By engineering the ideal ad for each unique query, we lifted click-through and quality scores dramatically — pulling in far more qualified traffic at a lower cost-per-click.

  • +70.59% CTR
  • 36.95% better CPC
  • +21.20% quality scores
  • 8.31× ad customization
  • 4.01× keyword depth
001252504755100queryDNA launchJanMarMayJulSepNovClicks (K)Click-through rate

Top-3 Student Loan Provider

No brand too big. No vertical too tough.

We shifted match strategy to capture the long tail others ignore — growing applications and slashing cost-per-application for one of the nation's largest student lenders.

  • +51.32% applications YOY
  • −22.06% cost-per-application
  • 61.49% from long-tail queries
001252503754100queryDNA launchJanMarMayJulSepNovApplications (K)Cost per application

Subscription · Nutritional Supplement

A full launch that nearly doubled order volume

With queryDNA optimization fully launched on a subscription nutritional-supplement model, year-over-year order volume jumped 93.33% — at a better cost-per-order.

  • +93.33% YOY order volume
  • −11.42% cost-per-order
0.000.290.5180.8261.035Full LaunchJunAugOctDecFebAprJunAugOctProjected orders (K)Projected CPL

All results at a glance

Every vertical, one method

queryDNA case-study outcomes by vertical (client identities generalized). Updated July 10, 2026.
VerticalHeadline resultSupporting results
National at-home healthcare provider+99.94% qualified requests/moAd spend −29.85% (−$164.6k/mo); cost/qualified request −64.91%; conversions +77.81%; CTR +14.37%; CPC −26.04%
Insurance lead aggregator+589.14% profitabilityLead volume +215.15%; cost-per-lead −4.50%
Lead generation (top-100 Google advertiser)+301.70% profitabilityLead volume +135.29%; cost-per-lead −18.32%
E-commerce+701.01% 5-year revenue72.26% average year-over-year revenue growth
National pediatric hospitals+70.59% CTRCPC 36.95% better; quality scores +21.20%; 8.31× ad customization; 4.01× keyword depth
Top-3 student loan provider+51.32% applications YOYCost-per-application −22.06%; 61.49% of volume from long-tail queries
Subscription nutritional supplement+93.33% YOY ordersCost-per-order −11.42%

queryDNA optimization: why the results repeat

Over the last decade plus, Search Engine Marketing has advanced to marked new heights and sophistication, yet the fundamentals have remained the same. Deliver the right search query, to the right keyword, with the right message, and on to the right landing page in order to maximize the opportunity to convert that user. That sounds simple, and it is — but achieving it every time, across the vast and shifting diversity of qualified search queries, is an immense feat. As a result, search engine marketers routinely and consistently come up short.

SEMoptimize built its practice around closing that gap: rebuilding the DNA of paid search at scale, where others manage the surface and call it strategy. Our queryDNA process, technology, and two decades of enterprise expertise make it possible to capitalize — at scale and with efficiency — on the complexity of paid search that others avoid for the sake of simplicity. The same data discipline now drives our SEO and GEO programs. The result: clients who routinely outgrow their competition, in both volume and efficiency.

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